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2025 a16z’s Big Ideas in Tech/
American Dynamism
- Nuclear resurgence: AI data centers will drive unprecedented demand for nuclear power, reviving decommissioned plants and spurring new reactor construction.
- Hardware-software jobs: Growing demand for engineers who can bridge hardware-software gaps in manufacturing, robotics, and industrial automation.
- Space frontier: Starship’s reusability advances will enable lifting larger payloads to space, from data centers to biomedical labs.
Bio + Health
- Common disease focus: Biotech startups will return to targeting major diseases, inspired by GLP-1 success.
- Health tech democratization: AI and wearables will give patients direct access to health insights.
- AI super staffing: AI models will help address healthcare staffing shortages by automating administrative work.
Consumer
- Specialized AI video: Video generation will become specialized for specific uses with better quality.
- AI memory banks: People will use AI to process their digital footprint for personal insights.
- Personalized knowledge work: AI will learn to match individual writing styles and workflows.
- Qualitative data analysis: AI will enable integration of unstructured data with quantitative analysis.
Crypto
- AI wallets: AI systems will manage their own crypto wallets and assets.
- Autonomous chatbots: Decentralized autonomous chatbots will emerge as independent entities.
- Proof of personhood: New systems will help verify human identity in an AI world.
- Crypto app stores: New distribution channels for crypto apps will emerge.
Enterprise + Fintech
- AI-powered compliance: Regulation-specific LLMs will simplify compliance processes.
- Service industry transformation: AI will help service businesses become more scalable.
- AI-native interfaces: New UI/UX paradigms will emerge for AI-powered software.
Games
- AI-native storytelling: A next-generation Pixar will emerge using AI for interactive experiences.
- Living AI companions: AI companions will develop more engaging personalities with virtual social networks.
- Faceless creators: AI will enable new forms of content creation with hidden identities.
Growth-stage Tech
- Search disruption: Google’s search monopoly will erode as AI chatbots gain market share.
- Sales renaissance: AI automation will lead to increased hiring of sales representatives.
Infrastructure
- AI computing centers: Nations will race to build massive AI compute facilities.
- Edge AI growth: Small, on-device AI models will become dominant for many applications.
- AI reasoning progress: Despite limitations, AI will advance in math, physics, and coding.